ORMDL3 anticorps (AA 53-81)

N° du produit ABIN7875600

L’anticorps anti-ORMDL3 Polyclonal Lapin est utilisé pour la détection de ORMDL3 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour ORMDL3 anticorps (AA 53-81) (ABIN7875600)

Antigène: ORMDL3 (ORM1-Like 3 (ORMDL3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORMDL3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ORMDL3 anticorps

Épitope: AA 53-81

Fonction: ORMDL3 Antibody / ORM1-like protein 3

Purification: Antigen affinity

Immunogène: A portion of amino acids 53-81 from the human protein was used as the immunogen for the ORMDL3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the ORMDL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ORMDL3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ORMDL3

Antigène: ORMDL3 (ORM1-Like 3 (ORMDL3))

Autre désignation: ORMDL3

Sujet: ORM1-like protein 3 is a protein that is encoded by the ORMDL3 gene. It belongs to a family of proteins known as ORM proteins, which play a crucial role in regulating the levels of sphingolipids - a class of lipids that are involved in various cellular processes. In particular, ORMDL3 has been shown to be a key player in the regulation of sphingolipid synthesis, and aberrant expression of this protein has been implicated in a number of diseases, including asthma. Recent studies have revealed that ORMDL3 plays a critical role in the development of asthma. It has been shown that individuals with certain genetic variations that result in increased ORMDL3 expression are at a higher risk of developing asthma. Additionally, ORMDL3 has been shown to be involved in the regulation of immune responses in the lungs, with increased levels of this protein leading to inflammation and airway hyperreactivity - hallmark features of asthma.

UniProt: Q8N138