GLUD1 / GLUD2 (AA 54-553) anticorps

N° du produit ABIN7875655

Cet anticorps anti-GLUD1 / GLUD2 Polyclonal Lapin (ABIN7875655) détecte spécifiquement GLUD1 / GLUD2 dans ELISA, WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GLUD1 / GLUD2 (AA 54-553) anticorps (ABIN7875655)

Antigène: GLUD1 / GLUD2

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 54-553

Fonction: GLUD1/2 Antibody / GDH1/2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids S54-A553) was used as the immunogen for the GLUD1/2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GLUD1/2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GLUD1/2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détail du antigène

Antigène: GLUD1 / GLUD2

Autre désignation: GLUD1/2

Sujet: This gene encodes Glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

UniProt: P00367