Recombinant alpha Sarcomeric Actin (AA 557-692) anticorps

N° du produit ABIN7875746

Cet anticorps Lapin Monoclonal détecte spécifiquement alpha Sarcomeric Actin dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant alpha Sarcomeric Actin (AA 557-692) anticorps (ABIN7875746)

Antigène: alpha Sarcomeric Actin

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ACTN2-7041R

Détail du produit

Épitope: AA 557-692

Fonction: Recombinant Sarcomeric Alpha Actinin Antibody / Alpha Actinin 2 / ACTN2

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 557-692 from the human protein was used as the immunogen for the recombinant Sarcomeric Alpha Actinin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Sarcomeric Alpha Actinin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Sarcomeric Alpha Actinin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: alpha Sarcomeric Actin

Autre désignation: Sarcomeric Alpha Actinin

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P35609