Emerin anticorps (AA 56-167)

N° du produit ABIN7875760

Cet anticorps anti-Emerin Monoclonal Souris (Clone EMD-2167) (ABIN7875760) détecte spécifiquement Emerin dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Emerin anticorps (AA 56-167) (ABIN7875760)

Antigène: Emerin (EMD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Emerin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EMD-2167

Détail du produit anti-Emerin anticorps

Épitope: AA 56-167

Fonction: Emerin Antibody

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 56-167 from the human protein was used as the immunogen for the Emerin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Titering of the Emerin antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Emerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Emerin

Antigène: Emerin (EMD)

Autre désignation: Emerin

Sujet: Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

UniProt: P50402