Calnexin anticorps (AA 560-592)
Aperçu rapide pour Calnexin anticorps (AA 560-592) (ABIN7875783)
Antigène
Voir toutes Calnexin (CANX) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 560-592
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Fonction
- Calnexin Antibody (C-Terminal Region)
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 560-592 from human Calnexin was used as the immunogen for the Calnexin antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Calnexin (CANX)
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Autre désignation
- Calnexin
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Sujet
- Calnexin is a calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. [UniProt]
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UniProt
- P27824
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Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
Antigène
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