EPH Receptor A3 anticorps (AA 59-514)

N° du produit ABIN7875906

L’anticorps anti-EPH Receptor A3 Polyclonal Lapin est utilisé pour la détection de EPH Receptor A3 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC (p), IF et FACS.

Aperçu rapide pour EPH Receptor A3 anticorps (AA 59-514) (ABIN7875906)

Antigène: EPH Receptor A3 (EPHA3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-EPH Receptor A3 anticorps

Épitope: AA 59-514

Fonction: Eph receptor A3 Antibody / EphA3

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D59-A514) was used as the immunogen for the Eph receptor A3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Eph receptor A3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Eph receptor A3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur EPH Receptor A3

Antigène: EPH Receptor A3 (EPHA3)

Autre désignation: Eph receptor A3

Sujet: Ephrin Receptor EphA3, is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1). Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases, PTKs), such as EPHA3, form a structurally related group of molecules that exhibit functional diversity. Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic. Many growth factor receptors are PTKs, e.g., the receptors for epidermal growth factor(EGFR), platelet-derived growth factor(PDGFR1,PDGFR2), colony-stimulating factor-1(CSF1R), and stem cell growth factor. The EPHA3 gene is mapped to 3p11.2. Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases. Within axial nerves, establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections.

UniProt: P29320

Pathways: Signalisation RTK, Regulation of Cell Size