BIRC3 anticorps (AA 59-88)
Aperçu rapide pour BIRC3 anticorps (AA 59-88) (ABIN7875913)
Antigène
Voir toutes BIRC3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 59-88
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Fonction
- BIRC3 Antibody
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 59-88 from the human protein was used as the immunogen for the BIRC3 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the BIRC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the BIRC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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Autre désignation
- BIRC3
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Sujet
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq].
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UniProt
- Q13489
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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