FBXO32 anticorps (AA 6-355)

N° du produit ABIN7875957

L’anticorps anti-FBXO32 Polyclonal Lapin est utilisé pour la détection de FBXO32 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour FBXO32 anticorps (AA 6-355) (ABIN7875957)

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO32 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-FBXO32 anticorps

Épitope: AA 6-355

Fonction: FBXO32 Antibody / F-box only protein 32 / Atrogin 1

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids Q6-F355) was used as the immunogen for the FBXO32 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the FBXO32 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the FBXO32 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur FBXO32

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Autre désignation: FBXO32

Sujet: F-box only protein 32, also known as MAFbx, for Muscle Atrophy F-box gene, and Atrogin-1, is a protein that in humans is encoded by the FBXO32 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q969P5