ROCK1 anticorps (AA 601-833)

N° du produit ABIN7876067

Cet anticorps Lapin Polyclonal détecte spécifiquement ROCK1 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour ROCK1 anticorps (AA 601-833) (ABIN7876067)

Antigène: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROCK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-ROCK1 anticorps

Épitope: AA 601-833

Fonction: Rho-associated protein kinase 1 Antibody / ROCK1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids K601-R833) was used as the immunogen for the Rho-associated protein kinase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Rho-associated protein kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Rho-associated protein kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ROCK1

Antigène: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Autre désignation: Rho-associated protein kinase 1

Sujet: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.

UniProt: Q13464

Pathways: Dynamique des Microtubules, Signalisation WNT, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling