alpha 2 Macroglobulin anticorps (AA 604-748)

N° du produit ABIN7876078

Cet anticorps anti-alpha 2 Macroglobulin Monoclonal Souris (Clone A2M-3623) (ABIN7876078) détecte spécifiquement alpha 2 Macroglobulin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour alpha 2 Macroglobulin anticorps (AA 604-748) (ABIN7876078)

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha 2 Macroglobulin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: A2M-3623

Détail du produit anti-alpha 2 Macroglobulin anticorps

Épitope: AA 604-748

Fonction: A2M Antibody / Alpha-2-Macroglobulin (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 604-748 from the human protein was used as the immunogen for the A2M antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the A2M antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the A2M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur alpha 2 Macroglobulin

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Autre désignation: A2M

Sujet: Alpha-2-Macroglobulin (A2M) is a homotetrameric serum protein consisting of four identical subunits that form dimers through disulfide bonds. Initially, it was characterized as a pan-proteinase inhibitor that was able to bait proteinases into cleaving specific peptide sequences on A2M. This interaction induces a conformational change, thus enabling it to trap the proteinase and further inhibit its activity. Subsequently, A2M has been shown to function as a carrier protein and regulator of cytokines during inflammation.

UniProt: P01023

Pathways: Lipid Metabolism