DLL4 anticorps (AA 608-641)
Aperçu rapide pour DLL4 anticorps (AA 608-641) (ABIN7876104)
Antigène
Voir toutes DLL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 608-641
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Fonction
- DLL4 Antibody (C-Terminal Region)
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 608-641 from human DLL4 was used as the immunogen for the DLL4 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the DLL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DLL4 (delta-Like 4 (DLL4))
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Autre désignation
- DLL4
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Sujet
- Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt]
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UniProt
- Q9NR61
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Pathways
- Signalisation Notch
Antigène
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