Pleiotrophin anticorps (AA 61-148)

N° du produit ABIN7876106

Cet anticorps Lapin Polyclonal détecte spécifiquement Pleiotrophin dans WB, ELISA, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Pleiotrophin anticorps (AA 61-148) (ABIN7876106)

Antigène: Pleiotrophin (PTN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Pleiotrophin anticorps

Épitope: AA 61-148

Fonction: HBBM Antibody / Heparin-binding brain mitogen / Pleiotrophin

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids D61-K148) was used as the immunogen for the HBBM antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PTN antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HBBM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: HBBM

Sujet: Pleiotrophin (PTN), also known as heparin-binding brain mitogen (HBBM), heparin-binding growth factor 8 (HBGF-8), neurite growth-promoting factor 1 (NEGF1), heparin affinity regulatory peptide (HARP), heparin binding growth associated molecule (HB-GAM) and Osteoblast-specific factor 1 (OSF-1), is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

UniProt: P21246

Pathways: Signalisation RTK