PCDHAC2 anticorps (AA 616-644)

N° du produit ABIN7876139

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHAC2 dans WB, FACS, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PCDHAC2 anticorps (AA 616-644) (ABIN7876139)

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHAC2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PCDHAC2 anticorps

Épitope: AA 616-644

Fonction: Protocadherin alpha-C2 Antibody / PCDHAC2

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 616-644 from the human protein was used as the immunogen for the Protocadherin alpha-C2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Protocadherin alpha-C2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Protocadherin alpha-C2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PCDHAC2

Antigène: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Autre désignation: Protocadherin alpha-C2

Sujet: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

UniProt: Q9Y5I4