SH3G2 anticorps (AA 65-292)

N° du produit ABIN7876278

L’anticorps anti-SH3G2 Polyclonal Lapin est utilisé pour la détection de SH3G2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour SH3G2 anticorps (AA 65-292) (ABIN7876278)

Antigène: SH3G2 (Endophilin-A1 (SH3G2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3G2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-SH3G2 anticorps

Épitope: AA 65-292

Fonction: Endophilin A1 Antibody / SH3GL2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R65-Q292) was used as the immunogen for the Endophilin A1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Endophilin A1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Endophilin A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SH3G2

Antigène: SH3G2 (Endophilin-A1 (SH3G2))

Autre désignation: Endophilin A1

Sujet: Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs (BAR) domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 (endophilin A1, SH3GL2) can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway.

UniProt: Q99962

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation