Gasdermin A anticorps (AA 66-94)

N° du produit ABIN7876353

L’anticorps anti-Gasdermin A Polyclonal Lapin est utilisé pour la détection de Gasdermin A dans des échantillons de Humain et Souris. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour Gasdermin A anticorps (AA 66-94) (ABIN7876353)

Antigène: Gasdermin A (GSDMA)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gasdermin A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Gasdermin A anticorps

Épitope: AA 66-94

Fonction: GSDMA Antibody / Gasdermin-A

Purification: Antigen affinity

Immunogène: A portion of amino acids 66-94 from the human protein was used as the immunogen for this GSDMA antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the GSDMA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4oC for up to one month. For long term, aliquot the GSDMA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Gasdermin A

Antigène: Gasdermin A (GSDMA)

Autre désignation: GSDMA

Sujet: Gasdermin-A is a protein that plays a crucial role in programmed cell death, or pyroptosis, a process that is essential for the body to eliminate infected or damaged cells. This protein acts as a pore-forming molecule, causing the cell membrane to rupture and release pro-inflammatory molecules that signal the immune system to clear away the debris. Recent studies have shown that dysregulation of Gasdermin-A can lead to a variety of health issues, including autoimmune diseases, inflammatory disorders, and even cancer.

UniProt: Q96QA5