NPR3 anticorps (AA 67-97)

N° du produit ABIN7876388

Cet anticorps Souris Polyclonal détecte spécifiquement NPR3 dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NPR3 anticorps (AA 67-97) (ABIN7876388)

Antigène: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp NPR3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NPR3 anticorps

Épitope: AA 67-97

Fonction: Natriuretic peptide receptor C Antibody / NPRC

Immunogène: A portion of amino acids 67-97 from the human protein was used as the immunogen for the Natriuretic peptide receptor C antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Natriuretic peptide receptor C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Natriuretic peptide receptor C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NPR3

Antigène: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Autre désignation: Natriuretic peptide receptor C

Sujet: Natriuretic peptide receptor C / NPRC is a receptor protein found in various tissues, including the heart, kidney, and blood vessels. Its main function is to bind to natriuretic peptides, which are hormones that help regulate blood pressure and fluid balance. When natriuretic peptides bind to Natriuretic peptide receptor C, they are degraded and their effects are blocked, leading to an increase in blood pressure. Natriuretic peptide receptor C also plays a role in the development of heart failure. Research has shown that increased levels of NPRC in the body can lead to impaired responses to natriuretic peptides, which in turn can contribute to the progression of heart failure. In addition to its role in cardiovascular health, NPRC has also been implicated in other diseases, such as obesity and diabetes. Studies have shown that NPRC levels are elevated in patients with these conditions, suggesting a potential link between Natriuretic peptide receptor C and metabolic disorders.

UniProt: P17342

Pathways: cAMP Metabolic Process