LTB anticorps (AA 68-306)
Aperçu rapide pour LTB anticorps (AA 68-306) (ABIN7876397)
Antigène
Voir toutes LTB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 68-306
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Fonction
- Lymphotoxin beta Antibody / Ltb
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived mouse recombinant protein (amino acids R68-G306) was used as the immunogen for the Lymphotoxin beta antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Lymphotoxin beta antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Lymphotoxin beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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Autre désignation
- Lymphotoxin beta
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Sujet
- Lymphotoxin-beta (LT-beta) also known as tumor necrosis factor C (TNF-C) is a protein that in humans is encoded by the LTB gene. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P41155
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Pathways
- Signalisation NF-kappaB
Antigène
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