RASL12 anticorps (AA 7-261)

N° du produit ABIN7876474

Cet anticorps anti-RASL12 Polyclonal Lapin (ABIN7876474) détecte spécifiquement RASL12 dans ELISA, WB, FACS, ICC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RASL12 anticorps (AA 7-261) (ABIN7876474)

Antigène: RASL12 (RAS-Like, Family 12 (RASL12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASL12 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-RASL12 anticorps

Épitope: AA 7-261

Fonction: RASL12 Antibody / Ras-like protein family member 12

Purification: Immunogen affinity purified

Immunogène: E.coli-derived human RASL12 recombinant protein (Position: K7-K261) was used as the immunogen for the RASL12 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RASL12 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RASL12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RASL12

Antigène: RASL12 (RAS-Like, Family 12 (RASL12))

Autre désignation: RASL12

Sujet: RASL12 antibody detects Ras-like protein family member 12, encoded by the RASL12 gene. Ras-like protein family member 12 is a small GTP binding protein that belongs to the Ras superfamily, which regulates signal transduction, cell growth, and cytoskeletal organization. RASL12 antibody provides researchers with a specific reagent for studying small GTPases and their influence on cellular signaling and differentiation.

Ras-like protein family member 12 is less well characterized than classical Ras proteins, but research using RASL12 antibody has shown that it retains the conserved GTP binding and hydrolysis domains characteristic of the Ras family. Through these domains, it likely regulates intracellular signaling cascades linked to growth, adhesion, and movement. Expression studies have shown that RASL12 is present in multiple tissues, suggesting broad cellular roles.

Studies with RASL12 antibody have revealed that Ras-like protein family member 12 may regulate cell cycle progression and survival pathways. Its sequence homology to other Ras proteins suggests involvement in MAPK and PI3K signaling networks, although specific effectors remain under investigation. Understanding the role of RASL12 may uncover new mechanisms of Ras family signaling and its impact on development and disease.

Dysregulation of RASL12 has been linked to tumor biology. Research using RASL12 antibody has demonstrated altered expression patterns in certain cancers, where imbalance may contribute to abnormal proliferation and survival. These findings support further investigation into its potential as a cancer biomarker and therapeutic target.

RASL12 antibody is commonly applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects endogenous expression in tissues and cell lines, immunohistochemistry reveals tissue-specific localization, and immunofluorescence highlights subcellular distribution. These approaches make RASL12 antibody valuable for research into Ras signaling networks.

By providing validated RASL12 antibody reagents, NSJ Bioreagents supports studies into Ras superfamily proteins, signal transduction, and cancer. Detection of Ras-like protein family member 12 offers researchers insight into how small GTPases integrate cellular signaling.

UniProt: Q9NYN1