Recombinant ACE2 anticorps (AA 705-805)

N° du produit ABIN7876592

Cet anticorps Lapin Monoclonal détecte spécifiquement ACE2 dans ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant ACE2 anticorps (AA 705-805) (ABIN7876592)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ACE2-8748R

Détail du produit anti-ACE2 anticorps

Épitope: AA 705-805

Fonction: Angiotensin Converting Enzyme 2 Antibody / ACE2

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 705-805) from the human protein was used as the immunogen for the Angiotensin Converting Enzyme 2 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Angiotensin Converting Enzyme 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Angiotensin Converting Enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: Angiotensin Converting Enzyme 2

Sujet: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour