SFRP1 anticorps (AA 730-1303)

N° du produit ABIN7876692

L’anticorps anti-SFRP1 Polyclonal Lapin est utilisé pour la détection de SFRP1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour SFRP1 anticorps (AA 730-1303) (ABIN7876692)

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-SFRP1 anticorps

Épitope: AA 730-1303

Fonction: FRP-1 Antibody / FRAP-related protein 1 / ATR

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids E730-A1303) was used as the immunogen for the FRP-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the FRP-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the FRP-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: FRP-1

Sujet: Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

UniProt: Q13535

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation