Fibrillarin anticorps (AA 77-138)

N° du produit ABIN7876758

L’anticorps anti-Fibrillarin Polyclonal Lapin est utilisé pour la détection de Fibrillarin dans des échantillons de Humain et Singe. Il a été validé pour WB, IF, ELISA et FACS.

Aperçu rapide pour Fibrillarin anticorps (AA 77-138) (ABIN7876758)

Antigène: Fibrillarin (FBL)

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Fibrillarin anticorps

Épitope: AA 77-138

Fonction: FBL Antibody / Fibrillarin

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids K77-N138) was used as the immunogen for the FBL antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the FBL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the FBL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: FBL

Sujet: RRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process