Ancient Ubiquitous Protein 1 anticorps (AA 77-399)

N° du produit ABIN7876763

Cet anticorps Lapin Polyclonal détecte spécifiquement Ancient Ubiquitous Protein 1 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ancient Ubiquitous Protein 1 anticorps (AA 77-399) (ABIN7876763)

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ancient Ubiquitous Protein 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Ancient Ubiquitous Protein 1 anticorps

Épitope: AA 77-399

Fonction: Ancient ubiquitous protein 1 Antibody / AUP1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids A77-R399) was used as the immunogen for the Ancient ubiquitous protein 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Ancient ubiquitous protein 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Ancient ubiquitous protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Ancient Ubiquitous Protein 1

Antigène: Ancient Ubiquitous Protein 1 (Aup1)

Autre désignation: Ancient ubiquitous protein 1

Sujet: Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene. The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

UniProt: Q9Y679