PIK3AP1 anticorps (AA 78-583)

N° du produit ABIN7876786

Cet anticorps anti-PIK3AP1 Polyclonal Lapin (ABIN7876786) détecte spécifiquement PIK3AP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PIK3AP1 anticorps (AA 78-583) (ABIN7876786)

Antigène: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3AP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PIK3AP1 anticorps

Épitope: AA 78-583

Fonction: PIK3AP1 Antibody

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids H78-R583) was used as the immunogen for the PIK3AP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PIK3AP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PIK3AP1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PIK3AP1

Antigène: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Autre désignation: PIK3AP1

Sujet: Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.

UniProt: Q6ZUJ8

Pathways: Activation of Innate immune Response, BCR Signaling, L'effet Warburg