GCKR anticorps (AA 8-569)
Aperçu rapide pour GCKR anticorps (AA 8-569) (ABIN7876839)
Antigène
Voir toutes GCKR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 8-569
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Fonction
- Glucokinase Regulator Antibody / GCKR
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Purification
- Affinity purified
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Immunogène
- An E. coli-derived human protein (amino acids Q8-Q569) was used as the immunogen for the Glucokinase Regulator antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Glucokinase Regulator antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Glucokinase Regulator antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Autre désignation
- Glucokinase Regulator
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Sujet
- The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
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UniProt
- Q14397
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Antigène
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