RASGRP1 anticorps (AA 8-678)

N° du produit ABIN7876843

Cet anticorps anti-RASGRP1 Polyclonal Lapin (ABIN7876843) détecte spécifiquement RASGRP1 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RASGRP1 anticorps (AA 8-678) (ABIN7876843)

Antigène: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RASGRP1 anticorps

Épitope: AA 8-678

Fonction: RASGRP1 Antibody / RAS guanyl-releasing protein 1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids R8-Q678) was used as the immunogen for the RASGRP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RASGRP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RASGRP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RASGRP1

Antigène: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Autre désignation: RASGRP1

Sujet: RAS guanyl-releasing protein 1 is a protein that in humans is encoded by the RASGRP1 gene. This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).

UniProt: O95267

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway