EPH Receptor A4 anticorps (AA 875-904)

N° du produit ABIN7877022

L’anticorps anti-EPH Receptor A4 Polyclonal Lapin est utilisé pour la détection de EPH Receptor A4 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour EPH Receptor A4 anticorps (AA 875-904) (ABIN7877022)

Antigène: EPH Receptor A4 (EPHA4)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EPH Receptor A4 anticorps

Épitope: AA 875-904

Fonction: Ephrin type-A receptor 4 Antibody / EphA4

Purification: SAS precipitation

Immunogène: A portion of amino acids 875-904 from the human protein was used as the immunogen for the Ephrin type-A receptor 4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Ephrin type-A receptor 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the Ephrin type-A receptor 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur EPH Receptor A4

Antigène: EPH Receptor A4 (EPHA4)

Autre désignation: Ephrin type-A receptor 4

Sujet: Ephrin type-A receptor 4, also known as Eph4A, is a member of the Eph receptor family. These receptors are involved in mediating cell-to-cell communication and are critical for various physiological processes such as tissue patterning, neuronal development, and immune response. One of the key functions of Eph4A is its role in axon guidance during neuronal development. Studies have shown that Eph4A is essential for establishing proper neuronal connections in the developing brain. Disruption of Eph4A signaling has been linked to various neurological disorders, highlighting the importance of this receptor in brain development. In addition to its role in neuronal development, Eph4A has also been implicated in cancer progression. Aberrant expression of Eph4A has been observed in various types of cancer, and targeting this receptor has shown promising results in inhibiting tumor growth and metastasis. Furthermore, Eph4A has been shown to play a role in immune response regulation. By modulating the activity of immune cells, Eph4A can influence the inflammatory response and contribute to the maintenance of immune homeostasis.

UniProt: P54764

Pathways: Signalisation RTK