FAF1 anticorps (AA 91-650)
Aperçu rapide pour FAF1 anticorps (AA 91-650) (ABIN7877143)
Antigène
Voir toutes FAF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 91-650
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Fonction
- FAS-associated factor 1 Antibody / FAF1
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids R91-E650) was used as the immunogen for the FAS-associated factor 1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the FAS-associated factor 1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the FAS-associated factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
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Autre désignation
- FAS-associated factor 1
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Sujet
- Fas-associated factor-1 (FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.
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UniProt
- Q9UNN5
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Pathways
- Maintenance of Protein Location
Antigène
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