GJB1 anticorps (AA 92-147)
Aperçu rapide pour GJB1 anticorps (AA 92-147) (ABIN7877153)
Antigène
Voir toutes GJB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 92-147
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Fonction
- GJB1 Antibody / Gap junction beta-1 protein / Connexin 32
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids A92-A147) was used as the immunogen for the GJB1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the GJB1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the GJB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Autre désignation
- GJB1
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Sujet
- Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene. This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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UniProt
- P08034
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Pathways
- Cell-Cell Junction Organization
Antigène
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