Claudin 7 anticorps (AA 92-211)

N° du produit ABIN7877154

L’anticorps anti-Claudin 7 Polyclonal Lapin est utilisé pour la détection de Claudin 7 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour Claudin 7 anticorps (AA 92-211) (ABIN7877154)

Antigène: Claudin 7 (CLDN7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Claudin 7 anticorps

Épitope: AA 92-211

Fonction: Claudin 7 Antibody

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids F92-V211) was used as the immunogen for the Claudin 7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Claudin 7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Claudin 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Claudin 7

Sujet: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

UniProt: O95471

Pathways: Hepatitis C