UNG anticorps (AA 96-313)

N° du produit ABIN7877249

Cet anticorps Lapin Polyclonal détecte spécifiquement UNG dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour UNG anticorps (AA 96-313) (ABIN7877249)

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNG est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-UNG anticorps

Épitope: AA 96-313

Fonction: UNG Antibody / Uracil-DNA Glycosylase

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids E96-L313) was used as the immunogen for the UNG antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the UNG antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the UNG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur UNG

Antigène: UNG (Uracil-DNA Glycosylase (UNG))

Autre désignation: UNG

Sujet: Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene, which has been confused with this gene, in the literature and some databases.

UniProt: P13051

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response