L’anticorps anti-PSPC1 Polyclonal Lapin est utilisé pour la détection de PSPC1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.
PSPC1
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the Paraspeckle component 1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the Paraspeckle component 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
PSPC1
(Paraspeckle Component 1 (PSPC1))
Autre désignation
Paraspeckle component 1
Sujet
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.