IRF5 anticorps (AA 98-477)

N° du produit ABIN7877286

L’anticorps anti-IRF5 Polyclonal Lapin est utilisé pour la détection de IRF5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour IRF5 anticorps (AA 98-477) (ABIN7877286)

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-IRF5 anticorps

Épitope: AA 98-477

Fonction: Interferon regulatory factor 5 Antibody / IRF5

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids R98-A477) was used as the immunogen for the Interferon regulatory factor 5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Interferon regulatory factor 5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Interferon regulatory factor 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IRF5

Antigène: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Autre désignation: Interferon regulatory factor 5

Sujet: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

UniProt: Q13568

Pathways: Signalisation TLR, Autophagy