Recombinant S100P anticorps (C-Term)
Aperçu rapide pour Recombinant S100P anticorps (C-Term) (ABIN7877471)
Antigène
Voir toutes S100P AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- C-Term
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Fonction
- Recombinant S100P Antibody (azide and preservative free)
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Purification
- Protein A affinity chromatography
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Immunogène
- A recombinant fragment corresponding to the C-terminal region of human S100P protein was used as the immunogen for the recombinant S100P antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the recombinant S100P antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant S100P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- S100P (S100 Calcium Binding Protein P (S100P))
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Autre désignation
- S100P
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Sujet
- S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
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UniProt
- P25815
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Pathways
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
Antigène
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