Recombinant S100P anticorps (C-Term)

N° du produit ABIN7877474

Cet anticorps Souris Monoclonal détecte spécifiquement S100P dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant S100P anticorps (C-Term) (ABIN7877474)

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100P est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RS100P-9254

Détail du produit anti-S100P anticorps

Épitope: C-Term

Fonction: Recombinant S100P Antibody / MIG9

Purification: Protein A/G affinity

Immunogène: A recombinant fragment corresponding to the C-terminus of human S100P/MIG9 protein was used as the immunogen for the recombinant S100P antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant S100P antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant S100P antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur S100P

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Autre désignation: S100P

Sujet: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D. S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins