Recombinant UBA3 anticorps (Catalytic Subunit)

N° du produit ABIN7877514

L’anticorps anti-UBA3 Monoclonal Lapin est utilisé pour la détection de UBA3 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Recombinant UBA3 anticorps (Catalytic Subunit) (ABIN7877514)

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp UBA3 est non-conjugé

Application: Western Blotting (WB)

Clone: 28U91

Détail du produit anti-UBA3 anticorps

Épitope: Catalytic Subunit

Fonction: UBA3 Antibody / Ubiquitin-activating enzyme 3 / UBE1C

Purification: Affinity chromatography

Immunogène: A synthetic peptide from human NEDD8-activating enzyme E1 catalytic subunit protein was used as the immunogen for the UBA3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the UBA3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the UBA3 antibody at -20oC.

Détails sur UBA3

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Autre désignation: UBA3

Sujet: NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]

UniProt: Q8TBC4