Recombinant YWHAE anticorps (full length)

N° du produit ABIN7877577

L’anticorps anti-YWHAE Monoclonal Lapin est utilisé pour la détection de YWHAE dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant YWHAE anticorps (full length) (ABIN7877577)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: YWHAE-8309R

Détail du produit anti-YWHAE anticorps

Épitope: full length

Fonction: 14-3-3 epsilon Antibody / YWHAE

Purification: Protein A/G affinity

Immunogène: Recombinant human full-length protein was used as the immunogen for the 14-3-3 epsilon antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the 14-3-3 epsilon antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the 14-3-3 epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: 14-3-3 epsilon

Sujet: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

UniProt: P62268

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase