Recombinant YWHAE anticorps (full length)

N° du produit ABIN7877579

Cet anticorps Souris Monoclonal détecte spécifiquement YWHAE dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant YWHAE anticorps (full length) (ABIN7877579)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RYWHAE-8860

Détail du produit anti-YWHAE anticorps

Épitope: full length

Fonction: Recombinant YWHAE Antibody / 14-3-3E

Purification: Protein A/G affinity

Immunogène: Recombinant human full-length protein was used as the immunogen for the recombinant YWHAE antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant YWHAE antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant YWHAE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: YWHAE

Sujet: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

UniProt: P62258

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase