Annexin a1 anticorps (full length)

N° du produit ABIN7877678

Cet anticorps Souris Monoclonal détecte spécifiquement Annexin a1 dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Annexin a1 anticorps (full length) (ABIN7877678)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ANXA1-1671

Détail du produit anti-Annexin a1 anticorps

Épitope: full length

Fonction: Annexin A1 Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human full-length protein was used as the immunogen for the Annexin A1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Annexin A1 antibody to be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Annexin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: Annexin A1

Sujet: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

UniProt: P04083

Pathways: Hormone Transport