Annexin A2 anticorps (full length)

N° du produit ABIN7877682

L’anticorps anti-Annexin A2 Monoclonal Souris est utilisé pour la détection de Annexin A2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Annexin A2 anticorps (full length) (ABIN7877682)

Antigène: Annexin A2 (ANXA2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin A2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3D5-4

Détail du produit anti-Annexin A2 anticorps

Épitope: full length

Fonction: ANXA2 Antibody / Annexin A2

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the ANXA2 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the ANXA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ANXA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Annexin A2

Antigène: Annexin A2 (ANXA2)

Autre désignation: ANXA2

Sujet: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

UniProt: P07355

Pathways: S100 Proteins