CA8 anticorps (full length)

N° du produit ABIN7877779

Cet anticorps anti-CA8 Monoclonal Souris (Clone CA8-6814) (ABIN7877779) détecte spécifiquement CA8 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CA8 anticorps (full length) (ABIN7877779)

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CA8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CA8-6814

Détail du produit anti-CA8 anticorps

Épitope: full length

Fonction: Carbonic Anhydrase VIII Antibody / CA8

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the Carbonic Anhydrase VIII antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the Carbonic Anhydrase VIII antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CA8

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: Carbonic Anhydrase VIII

Sujet: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

UniProt: P35219