CPA1 anticorps (full length)

N° du produit ABIN7877813

Cet anticorps Souris Monoclonal détecte spécifiquement CPA1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CPA1 anticorps (full length) (ABIN7877813)

Antigène: CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CPA1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CPA1-2712

Détail du produit anti-CPA1 anticorps

Épitope: full length

Fonction: Carboxypeptidase A1 Antibody / CPA1

Purification: Protein G affinity

Immunogène: Full length recombinant human protein was used as the immunogen for the Carboxypeptidase A1 antibody.

Isotype: IgG2c, kappa

Information d'application

Indications d'application: Optimal dilution of the Carboxypeptidase A1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Carboxypeptidase A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CPA1

Antigène: CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

Autre désignation: Carboxypeptidase A1

Sujet: Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

UniProt: P15085