CD34 anticorps (full length)

N° du produit ABIN7877864

Cet anticorps Souris Monoclonal détecte spécifiquement CD34 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD34 anticorps (full length) (ABIN7877864)

Antigène: CD34

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CD34-4939

Détail du produit anti-CD34 anticorps

Épitope: full length

Fonction: CD34 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human HPCA1 protein was used as the immunogen for the CD34 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CD34 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the CD34 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet: This MAb recognizes a single chain, transmembrane,heavily glycosylated protein of 90-120 kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intothree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidasebut sensitive to glycoprotease and chymopapain.CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85 % of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.

UniProt: P28906