Recombinant Cyclin B1 anticorps (full length)
Aperçu rapide pour Recombinant Cyclin B1 anticorps (full length) (ABIN7878061)
Antigène
Voir toutes Cyclin B1 (CCNB1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Cyclin B1 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human CCNB1 protein was used as the immunogen for the Cyclin B1 antibody.
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Isotype
- IgG, kappa
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anti-Cyclin B1 (CCNB1) (C-Term) antibody
CCNB1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) antibodyCCNB1 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) antibodyCCNB1 Reactivité: Humain, Souris IHC Hôte: Souris Monoclonal CCNB1-1098 unconjugated
anti-Cyclin B1 (CCNB1) (C-Term) antibodyCCNB1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) (AA 1-21) antibodyCCNB1 Reactivité: Humain, Souris, Hamster WB, IHC, FACS, IP, BI, FM Hôte: Souris Monoclonal GNS-1 unconjugated
anti-Cyclin B1 (CCNB1) (AA 1-433) antibodyCCNB1 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) (AA 271-433) antibodyCCNB1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) antibodyKD Validated CCNB1 Reactivité: Humain WB, FACS, ICC Hôte: Lapin Monoclonal 23GB1670 unconjugated Recombinant Antibody
anti-Cyclin B1 (CCNB1) (AA 1-383) antibodyCCNB1 Reactivité: Humain, Souris, Rat WB, IHC, IF, ELISA, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-Cyclin B1 (CCNB1) (AA 1-433) antibodyCCNB1 Reactivité: Humain WB, IF, FACS, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal dilution of the Cyclin B1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Cyclin B1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cyclin B1 (CCNB1)
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Autre désignation
- Cyclin B1
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Sujet
- It recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.
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UniProt
- P14635
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Pathways
- Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
Antigène
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