Desmin anticorps (full length)
Aperçu rapide pour Desmin anticorps (full length) (ABIN7878128)
Antigène
Voir toutes Desmin (DES) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Desmin Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human desmin protein was used as the immunogen for the Desmin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the Desmin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Desmin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Desmin (DES)
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Autre désignation
- Desmin
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Sujet
- Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
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UniProt
- P17661
Antigène
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