Recombinant Desmocollin 2+3 (full length) anticorps

N° du produit ABIN7878136

Cet anticorps anti-Desmocollin 2+3 Monoclonal Lapin (Clone DSC2-9165R) (ABIN7878136) détecte spécifiquement Desmocollin 2+3 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Desmocollin 2+3 (full length) anticorps (ABIN7878136)

Antigène: Desmocollin 2+3

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: DSC2-9165R

Détail du produit

Épitope: full length

Fonction: Recombinant Desmocollin-2/3 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human DSC2 protein was used as the immunogen for the recombinant Desmocollin-2/3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the recombinant Desmocollin-2/3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Desmocollin-2/3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: Desmocollin 2+3

Autre désignation: Desmocollin-2/3

Sujet: Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. The desmosome is subdivided into two regions. The plaque region lies adjacent to the plasma, and is believed to contain molecules that attach the intermediate filament cytoskeleton to the desmosome. The core region is composed of transmembrane glycoproteins that are thought to mediate cell-cell adhesion. Desmogleins and desmocollins are the main desmosomal transmembrane proteins. These desmosomal glycoproteins belong to the members of the cadherin family of adhesion molecules. Three different isoforms of both desmogleins and desmocollins have been identified, named as desmoglein 1-3 and desmocollins. Desmosomal cadherins showed differentiation-specific expression in the human epidermis, although the functional significance of this differential expression is not fully understood. Desmocollin-1 can be found in the upper layers. The expression of desmocollin-2 varies in the basal and suprabasal layers. And desmocollin-3 is expressed more evenly throughout the suprabasal layers.

UniProt: Q02487