GTF2B anticorps (full length)
Aperçu rapide pour GTF2B anticorps (full length) (ABIN7878278)
Antigène
Voir toutes GTF2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
-
-
Épitope
- full length
-
Fonction
- TFIIB Antibody / GTF2B (azide and preservative free)
-
Purification
- Protein A/G affinity
-
Immunogène
- Recombinant full-length human protein was used as the immunogen for the TFIIB antibody.
-
Isotype
- IgG2b
-
-
-
-
Indications d'application
- Optimal dilution of the TFIIB antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the TFIIB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- GTF2B (General Transcription Factor IIB (GTF2B))
-
Autre désignation
- TFIIB
-
Sujet
- In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH, and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Template commitment is established by the initial binding of TFIID to the TATA element of the promotor, a step which may be facilitated by TFIIA. TFIIB then acts as the bridge between TFIID and RNA polymerase II.
-
UniProt
- Q00403
Antigène
-