Recombinant KRT17 anticorps (full length)

N° du produit ABIN7878487

Cet anticorps anti-KRT17 Monoclonal Lapin (Clone KRT17-7155R) (ABIN7878487) détecte spécifiquement KRT17 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant KRT17 anticorps (full length) (ABIN7878487)

Antigène: KRT17 (Keratin 17 (KRT17))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT17 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT17-7155R

Détail du produit anti-KRT17 anticorps

Épitope: full length

Fonction: Keratin 17 Antibody / Cytokeratin 17 / CK17

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human KRT17 protein was used as the immunogen for the Keratin 17 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Keratin 17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Keratin 17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur KRT17

Antigène: KRT17 (Keratin 17 (KRT17))

Autre désignation: Keratin 17

Sujet: Cytokeratin 17 (CK17) is normally expressed in the basal cells ofcomplex epithelia but not in stratified orsimple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glandssuch as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. Additionally, anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.

UniProt: Q04695