Recombinant MUC5AC anticorps (full length)

N° du produit ABIN7878645

L’anticorps anti-MUC5AC Monoclonal Lapin est utilisé pour la détection de MUC5AC dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant MUC5AC anticorps (full length) (ABIN7878645)

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC5AC est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: MUC5AC-7066R

Détail du produit anti-MUC5AC anticorps

Épitope: full length

Fonction: Recombinant Mucin 5AC Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human protein was used as the immunogen for the recombinant Mucin 5AC antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the recombinant Mucin 5AC antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Mucin 5AC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUC5AC

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Autre désignation: Mucin 5AC

Sujet: Mucins are a group of high molecular weight glycoproteins consisting of a mucin core protein and O-linked carbohydrates. Mucin 5AC is a gel-forming mucin that is secreted from surface mucous cells. Glucocorticoid is required for the expression of Mucin 5AC mRNA and high doses of hydrocortisone suppresses its expression. Additionally, asthmatic fluid stimulates Mucin 5AC synthesis several-fold. The pro-inflammatory cytokines IL-6 and TNFi± stimulate Mucin 5AC secretion and thus contribute to the upregulation of mucin by chronic inflammation. Expression of Mucin 5AC is retinoic acid (RA)- or retinol-dependent, and RA control of mucin genes is mediated by the retinoid acid receptor RARi± and, to a lesser extent, by RARi³.

UniProt: P98088