MEF2B anticorps (full length)

N° du produit ABIN7878686

Cet anticorps Souris Monoclonal détecte spécifiquement MEF2B dans WB, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MEF2B anticorps (full length) (ABIN7878686)

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEF2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-MEF2B-2F9

Détail du produit anti-MEF2B anticorps

Épitope: full length

Fonction: MEF2B Antibody

Purification: Protein A/G affinity

Immunogène: Recombinant full-length human MEF2B protein was used as the immunogen for the MEF2B antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the MEF2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MEF2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MEF2B

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Autre désignation: MEF2B

Sujet: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

UniProt: Q02080