MYCN anticorps (full length)

N° du produit ABIN7878701

Cet anticorps Souris Monoclonal détecte spécifiquement MYCN dans WB et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MYCN anticorps (full length) (ABIN7878701)

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Classe de qualité: Carrier-free

Clone: NMYC-1

Détail du produit anti-MYCN anticorps

Épitope: full length

Fonction: n-Myc Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant full-length human n-Myc protein was used as the immunogen for the n-Myc antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the n-Myc antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the n-Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: n-Myc

Sujet: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

UniProt: P04198